(1) During manic periods there are unusually high levels of norepinephrine and serotonin while, during depressed periods, there are unusually low levels.
(1) The biological explanation is also supported by strong genetic inheritance.
(4) In addition, many clinicians have difficulty first differentiating between bipolar I and bipolar II.
Since the types of patients, lengths of episodes, and age of onset are very similar, the only diagnostic tool is the difference between mania and hypomania.
Most recently in a manic episode with at least one previous major depressive episode, manic episode, or mixed episode 4.
Most recently a mixed episode with at least one previous major depressive episode, manic episode, or mixed episode.
It is important to note that, except for the last symptom, all of these symptoms must be present nearly every day.
(2, 7) In addition to major depressive episodes, patients with manic depression also feel periods of hypomania.
The affected person may not mind the mania or may be in denial of the disease, and since it only lasts a few hours, no one else may even notice.
(4) By the time people actually begin to notice the manic-depressive cycle (or just the mania) it has already reached a point where the patient is barely able to function normally.